Home About KLEAN - PREP® About Bowel Cleansing Evidence of Efficacy Q&A

What is Klean-Prep®?
The preparation of the colon prior to colonoscopy and X-ray is an important procedure before diagnostic examinations.
Up to 20%-30% of incomplete colonoscopies are a consequence of inadequate bowel cleansing1.
Klean-Prep®  is a balanced mixture of polyethylene glycol 3350 (PEG 3350) and electrolytes which, added to water, produces a clear, colourless, iso-osmotic solution. It acts as a bowel cleansing agent and allows total cleansing in 4 to 6 hours.
Klean-Prep®  can be taken at home and thus reduces hospitalization and nursing time. It has a high cleansing success rate (95%) and is very well tolerated.
Klean-Prep®  is the only product of its class which provides patients with an easy-to-use tub for the preparation and intake of the solution.

Who is Helsinn?
Helsinn Healthcare is a privately owned Swiss pharmaceutical company founded in 1976. Helsinn's strategy focuses on developing and licensing innovative drugs and medical devices. Helsinn distributes Klean-Prep®  under licenses through an international network of selected partners. For further information see www.helsinn.com.

Where is Klean-Prep® marketed?
Helsinn acquired world-wide rights to KLEAN-PREP® excluding Canada from Helix Biopharma in 1990 and has then developed and licensed-out the product to a number of partners in Europe, North America, Latin America, Africa, Middle and Far East (please click here for more information).

Klean-Prep®  is presently marketed under the same brand name in more than 30 countries. In these markets, Klean-Prep®  has achieved excellent sales performance and it is among the leaders in bowel cleansing preparations, thanks to the recognised quality of the product combined with partnerships with companies well introduced in hospitals and diagnostic centres.

In which packs is Klean-Prep® available?
Klean-Prep®  is the only product of its class which provides patients with an and easy-to-use tub for the preparation and intake of the solution.
Klean-Prep®  is available in the following packs:

  • Four sachets in carton, tub, transit pack (for mailing)
  • Loose sachets carton (for hospitals)
  • Flavour sachets available separately

How should Klean-Prep® be used?
Klean-Prep®  is for oral administration only.
For adults: the usual dose is 4 litres of the reconstituted solutions of 4 sachets consumed at a rate of 250 ml every 10 to 15 minutes until the total volume is consumed or rectal effluent is clear.
For children: There is no recommended dosage for children.

Can Klean-Prep® be used during pregnancy and lactation?
The preparation should only be used during pregnancy and lactation if considered essential by the physician. There is no experience of use during pregnancy. The purpose and mechanisms of use should be borne in mind if the physician is considering administration.

What about Klean-Prep® safety ?
Preclinical studies provide evidence that polyethylene glycol 3350 has no significant systemic toxicity potential.




1Turner D. et al, Evidence-based recommendations for bowel cleansing before colonoscopy in children: a report from a national working group. 


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